Product Details
»Book Publisher: CRC (15 January, 2002)
»ISBN: 0824706358
»Book author: Kim Lewis, Abigail Salyers, Harry Taber, Richard G. Wax
Book Description:
Focusing on combating bacterial pathogens by understanding their strategies of defense, this book highlights the antibiotic resistance in pathogens that poses the greatest threat to human health. Each chapter begins with a summary of concepts, so those not actively working in the field gain an overall picture of what follows. Containing nearly 2000 references for additional research, the book presents the molecular basis, methods of detection and identification, and concepts for reducing the development and spread of resistant bacterial strains. It has been called “a useful reference book”, and “a comprehensive and straightforward guide” by The Bulletin of the Royal College of Pathologies.Contents
Foreword Myron E. Wegman
Preface
Contributors
A Historical Introduction William C. Summers
1. The Ecology of Antibiotic Resistance Genes
Abigail A. Salyers, Nadja B. Shoemaker, and George T. Bonheyo
2. Antibiotic Resistance: How Bacterial Populations
Respond to a Simple Evolutionary Force
Fernando de la Cruz, Juan M. Garc´ıa-Lobo, and Julian Davies
3. Global Response Systems That Cause Resistance
Paul F. Miller and Philip Rather
4. Drug Efflux
Kim Lewis and Olga Lomovskaya
5. Mechanisms of Aminoglycoside Antibiotic Resistance
Gerard D. Wright
6. _-Lactamases and Resistance to _-Lactam Antibiotics
Lakshmi P. Kotra, Jean-Pierre Samama,
and Shahriar Mobashery
7. Target Modification as a Mechanism of Antimicrobial
Resistance
David C. Hooper
8. Antibiotic Permeability
Harry W. Taber
9. Phenotypic Tolerance of Bacteria
Rodger Novak and Elaine I. Tuomanen
10. Resistance as a Worldwide Problem
Rosamund Williams
11. Genetic Methods for Detecting Bacterial Resistance
Genes
Amalio Telenti and Fred C. Tenover
12. Evolution and Epidemiology of Antibiotic-Resistant
Pneumococci
Christopher Gerard Dowson and Krzysztof Trzci ´ nski
13. Resistance Problems Associated with the Enterococcus
George M. Eliopoulos
14. Methicillin Resistance in Staphylococcus aureus
Keeta S. Gilmore, Daniel F. Sahm, and Michael S. Gilmore
15. Drug Resistance and Tuberculosis Chemotherapy—From
Concept to Genomics
Alexander S. Pym and Stewart T. Cole
16. Antibiotic Resistance in Enterobacteria
Nafsika H. Georgopapadakou
17. Public Health Responses to Antimicrobial Resistance in
Outpatient and Inpatient Settings
Richard E. Besser, Julia Y. Morita, and Scott K. Fridkin
18. Approaches to New Antimicrobial Targets in the Age of
Genomics
