The Comprehensive Sourcebook of Bacterial Protein Toxins, Third Edition
by Joseph E. Alouf (Editor), Michel R. Popoff (Editor)
Product Details:
* Hardcover: 1072 pages
* Publisher: Academic Press; 3 edition (December 19, 2005)
* Language: English
* ISBN-10: 0120884453
Book Description:
Every medical school and university library must have a copy...it will be a worthwhile investment and a treasure trove of information.
- Cyril J. Smith, Trinity College Dublin, Ireland for CLINICAL INFECTIOUS DISEASES (Sept 2006)
Contents
Contributors xi
Preface to Third Edition xvii
Joseph E. Alouf and Michel R. Popoff
Preface to Second Edition xix
Joseph E. Alouf and John H. Freer
Preface to First Edition xxi
Joseph E. Alouf and John H. Freer
Introduction xxiii
R. John Collier
INTRODUCTORY SECTION
1. A116-year story of bacterial protein toxins (1888–2004): from “diphtheritic poison”
to molecular toxinology 3
Joseph E. Alouf
SECTION I: BASIC GENOMIC AND PHYSIOLOGICAL ASPECTS OF
BACTERIAL PROTEIN TOXINS
2. Evolutionary aspects of toxin-producing bacteria 25
Brenda A. Wilson and Mengfei Ho
3. Mobile genetic elements and pathogenicity islands encoding bacterial toxins 44
Ulrich Dobrindt and Jörg Hacker
4. Regulation systems of toxin expression 64
Camille Locht, Didier Lereclus, Julian I. Rood, and Bénédicte Fournier
5. Toxin secretion systems 83
Maria Scott and Maria Sandkvist
6. Toxin receptors 106
Yasuhiko Horiguchi and Eisuke Mekada
7. Translocation of bacterial protein toxin into the cytosol 120
Sjur Olsnes and Jørgen Wesche
8. Intracellular trafficking of bacterial and plant protein toxins 135
Christophe Lamaze and Ludger Johannes
9. Bacterial toxins and virulence factors targeting the actin cytoskeleton and intercellular junctions 154
Michel R. Popoff and Bradley G. Stiles
10. Bacterial toxins and mitochondria 188
Antoine Galmiche and Patrice Boquet
11. Toxins activating Rho GTPases and exploiting the cellular ubiquitin/proteasome machineries 202
Michel Gauthier, Gilles Flatau, Patrice Boquet, and Emmanuel Lemichez
SECTION II: BACTERIAL PROTEIN TOXINS ACTING IN THE
INTRACELLULAR COMPARTMENT OF EUKARYOTIC CELLS
12. Molecular, functional, and evolutionary aspects of ADP-ribosylating toxins 213
Vega Masignani, Mariagrazia Pizza, and Rino Rappuoli
13. Diphtheria toxin 245
Diana Marra Oram and Randall K. Holmes
14. Pseudomonas aeruginosa toxins 257
Anthony W. Maresso, Dara W. Frank, and Joseph T. Barbieri
15. Vibrio cholerae and Escherichia coli thermolabile enterotoxin 270
Timothy R. Hirst and Jocelyne M. D’Souza
16. Bordetella protein toxins 291
Jiri Masin, Peter Sebo, and Camille Locht
17. The Shiga toxins: properties and action on cells 310
Kirsten Sandvig
18. Bacillus anthracis toxins 323
Stephen H. Leppla
19. Attack of the nervous system by clostridial toxins: physical findings, cellular and molecular actions 348
Bernard Poulain, Bradley G. Stiles, Michel R. Popoff, and Jordi Molgo
20. Uptake and transport of clostridium neurotoxins 390
Stephanie Bohnert, Kartrin Deinhardt, Sara Salinas, and Giampietro Schiavo
21. Large clostridial cytotoxins modifying small GTPases 409
Maja Rupnik and Ingo Just
22. Pasteurella multocida toxin 430
Brenda A. Wilson and Mengfei Ho
23. Cytolethal distending toxins 448
Monica Thelestam and Teresa Frisan
24. Helicobacter pylori vacuolating toxin 468
Mark S. McClain and Timothy L. Cover
25. Escherichia coli heat-stable enterotoxin b 491
J. Daniel Dubreuil
SECTION III: TOXINS ACTING ON THE SURFACE OF TARGET CELLS
(EXCEPT SUPERANTIGENS)
26. Paradigms and classification of bacterial membrane-damaging toxins 507
Joseph E. Alouf
27. Membrane-damaging and cytotoxic phospholipases 516
Richard W. Titball and Ajit K. Basak
28. Bacteroides fragilis toxins 535
Cynthia L. Sears, Augusto A. Franco, and Shaoguang Wu
29. Structure and mode of action of RTX toxins 547
Albrecht Ludwig and Werner Goebel
30. Genetics and phylogeny of RTX cytolysins 570
Joachim Frey
31. The family of two-component cytolysins of Serratia and other bacteria 578
Volkmar Braun and Ralf Hertle
32. Alpha-helix and beta-barrel pore-forming toxins
(leucocidins, alpha-, gamma-, and delta-cytolysins) of Staphylococcus aureus 590
Gilles Prévost, Lionel Mourey, Didier A. Colin, Henri Monteil, Mauro Dalla Serra, and Gianfranco Menestrina†
33. Aerolysin and related Aeromonas toxins 608
Laure Gurcel, Ioan Iacovache, and F. Gisou van der Goot
34. Clostridium septicum pore-forming á-toxin 623
Jody Melton and Rodney K.Tweten
35. Clostridium perfringens å-toxin 631
Ajit K. Basak, M. Popoff, R.W. Titball, and Ambrose Cole
36. Repertoire and general features of the family of cholesterol-dependent cytolysins 643
Joseph E. Alouf, Stephen J. Billington, and B. Helen Jost
37. Comparative three-dimensional structure of cholesterol-dependent cytolysins 659
Galina Polekhina, Susanne C. Feil, Julian Tang, Jamie Rossjohn, Kara Sue Giddings, Rodney K. Tweten,
and Michael W. Parker
38. Perfringolysin O and intermedilysin: mechanisms of pore formation by the cholesterol-dependent
cytolysins 671
Kara S. Giddings, Arthur E. Johnson, and Rodney K. Tweten
39. Pneumolysin: structure, function, and role in disease 680
Tim J. Mitchell
40. Listeriolysin 700
José A. Vázquez-Boland, Radek Stachowiak, Lizeth Lacharme, and Mariela Scortti
41. Enterococcus faecalis cytolysin toxin 717
Karen Carniol and Michael S. Gilmore
42. Streptolysin S: one of the most potent and elusive of all bacterial toxins 728
Joyce C.S. de Azavedo, Kowthar Y. Salim, and Darrin J. Bast
43. The group B streptococcal â-hemolysin/cytolysin 737
George Y. Liu and Victor Nizet
44. Hemolysins of vibrio cholerae and other vibrio species 748
Sumio Shinoda and Shin-ichi Miyoshi
45. Clostridium perfringens enterotoxin 763
Bruce A. McClane
46. Bacillus cereus enterotoxins, bi- and tricomponent cytolysins, and other hemolysins 779
Nathalie Michelet, Per Einar Granum, and Jacques Mahillon
47. Uropathogenic Escherichia coli cytolysins 791
Tobias A. Oelschlaeger and Jörg Hacker
48. Escherichia coli, Vibrio, and Yersinia species heat-stable enterotoxins 798
J. Daniel Dubreuil
SECTION IV: SUPERANTIGENIC TOXINS
49. What are superantigens? 821
Joseph E. Alouf and Heide Müller-Alouf
50. Staphylococcal superantigens and the diseases they cause 830
Takehiko Uchiyama, Ken’ichi Imanishi, Tohru Miyoshi-Akiyama, and Hidehito Kato
51. Streptococcal superantigenic toxins 844
Thomas Proft and John D. Fraser
52. The Superantigenic toxin of Yersinia Pseudotuberculosis 862
Christophe Carnoy, Nadine Lemaitre, and Michel Simonet
53. Comparative three-dimensional structure of bacterial superantigenic toxins 872
Matthew D. Baker and K. Ravi Acharya
SECTION V: CLINICAL, IMMUNOLOGICAL ASPECTS AND
APPLICATIONS OF BACTERIAL PROTEIN TOXINS IN CELL
BIOLOGY AND THERAPY
54. Induction and modulation of inflammatory networks by bacterial protein toxins 887
Steffen Backert, Wolfgang König, Ralf Arnold, and Brigitte König
55. Clostridial toxins in the pathogenesis of gas gangrene 919
Amy E. Bryant and Dennis L. Stevens
56. Staphylococcal exfoliative toxins 930
Shamez N. Ladhani
57. Bacterial toxins as food poisons 949
Per Einar Granum
58. Medical applications of botulinum neurotoxins 959
Eric A. Johnson, Gary E. Borodic, and Martin A. Acquadro
59. Toxins as tools 976
Klaus Aktories
60. Engineering of bacterial toxins for research and medicine 991
Aurélie Perier, Alexandre Chenal, Aurélie Babon, André Ménez, and Daniel Gillet
61. Engineered bacterial toxin vaccines and adjuvants 1008
Jan Holmgren and Ann-Mari Svennerholm
62. Bacterial protein toxins as biological weapons 1019
Leonard A. Smith
Index 1031
