Product Details
»Book Publisher: CRC (30 October, 2006)
»ISBN: 0824754077
»Book author: Shayne C. Gad
Book Description:
Reflecting a decade’s worth of changes, this second edition is a practical guide to the common statistical problems encountered in toxicology and the methodologies that are available to solve them. The book presents a historical review of the use of animal models used in toxicology and an overview of broad considerations of metabolism and its relevance. Chapters covering the eight major species used in toxicology and experimental biology form the core of the book. With contributions from experts in toxicology, toxicological pathology, and species-specific metabolism, each of these chapters provide an excellent introductory “course” along with guidance to the literature for more detailed understanding.
Contents
Chapter 1
Introduction
Shayne C. Gad
Chapter 2
The Mouse
Toxicology
Shayne C. Gad
Pathology
Charles H. Frith, Dawn G. Goodman, and Byron G. Boysen
Metabolism
Shayne C. Gad
Chapter 3
The Rat
Toxicology
Mark D. Johnson
Pathology
Shayne C. Gad
Metabolism
Shayne C. Gad
Chapter 4
The Hamster
Toxicology
Shayne C. Gad
Pathology
Frederick G. Hess
Metabolism
Shayne C. Gad
Chapter 5
The Guinea Pig
Toxicology
Shayne C. Gad
Pathology
John C. Peckham
Metabolism
Shayne C. Gad
Chapter 6
The Rabbit
Toxicology
Clare M. Salamon and Karen M. MacKenzie
Pathology
John C. Peckham
Metabolism
Shayne C. Gad
Chapter 7
The Ferret
Toxicology
Daniel E. McLain
Pathology
Sundeep Chandra
Metabolism
Shayne C. Gad
Chapter 8
The Dog
Toxicology
Gillian C. Haggerty
Pathology
John C. Peckham and Robert W. Thomassen
Metabolism
Shayne C. Gad
Chapter 9
Primates
Toxicology
Mark D. Walker, Joyce K. Nelson, and John C. Bernal
Pathology
Gary B. Baskin
Metabolism
Shayne C. Gad
Chapter 10
The Minipig
Toxicology
Shayne C. Gad
Pathology
Zuhal Dincer and Ove Svendsen
Metabolism
Mette Tingleff Skaanild
Chapter 11
Alternative Species
Shayne C. Gad
Chapter 12
Clinical Pathology of Laboratory Animals
Robert L. Hall
Chapter 13
Model Selection and Scaling
Shayne C. Gad
Chapter 14
Susceptibility Factors
Shayne C. Gad
Chapter 15
Laws and Regulations Governing Animal Care and Use in Research
Shayne C. Gad
Appendix
Commercial Sources of Laboratory Animals
Shayne C. Gad
Index
